We use cookies to provide visitors of our website with the best possible experience. To learn more how we use cookies or how to block cookies, please visit our cookie policy.



Genotoxicity refers to the destructive effects of mutagens such as high energy radiation and chemicals on cellular nucleic acids, particularly nuclear DNA. Single cell gel electrophoresis, or the comet assay, can be used to probe DNA fracture by mutagens and the g-H2AX immunofluorescence assay can used to quantify DNA double strand breaks. Each method has its challenges with respect to image analysis, but Gen5 3.0 has the ability to quantify either the %DNA in the comet tail or comet tail moment; or count g-H2AX foci to determine levels of genotoxicity.


Application Notes:


Related Webinars:


Related Products:


Learn more about Genotoxicity applications - search our Application Notes and technical documentation in Resources.


Get more info