Resources
Руководства по примнению
Статьи по применению
- Automation of a HTRF® Universal Methyltransferase Assay (December 23, 2014)
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A Novel Food Freshness Assay Based on ATP Depletion
Part 2: Challenge Testing of the Automated Assay (August 13, 2014) -
A Novel Food Freshness Assay Based on ATP Depletion
Part 1: Automation and Sample Prep Optimization (August 8, 2014) - Live Cell Biosensor Assay Used To Interrogate GPCRs - Comparative Analysis of Biosensor Variants (November 8, 2013)
- Automation of a Homogeneous Proximity Assay for Immunogenicity Testing of Biological Drug Products (June 5, 2013)
- Assessment of HDAC1 Inhibition Using an Automated, Bioluminescent Histone Deacetylase I/II Assay (March 27, 2013)
- Automation of Optimiser™ Microplate Technology for High Throughput Applications (March 13, 2013)
- An Automated DELFIA ADCC Assay Method using a CD16.NK-92 Cell Line (March 7, 2013)
- Interrogation of SET7/9 Histone Lysine Methyltransferase Using a High Throughput Fluorescence Polarization Screening Assay (February 12, 2013)
- BRD4 Bromodomain 1 Inhibitor Screening using a Homogeneous Proximity Assay (February 11, 2013)
- Automating a Direct, Cell-Based, Target-Compound Interaction Assay for G9a Histone Methyltransferase and Bromodomain Proteins (February 8, 2013)
- Automated Bioluminescent ADCC Reporter Bioassay Using Bioengineered Jurkat Cells (February 8, 2013)
- Automated, High Throughput Methods for the Quantification of Endogenous Cellular Kinase Activity using HTRF Technology (January 28, 2013)
- Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library (August 7, 2012)
- Automated High Throughput Functional Cell-based Bioassays for EGFR Blocking Antibodies (June 7, 2012)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (May 16, 2012)
- A Semi-Automated, Non-Radioactive Assay for the Detection of Antibody-Based Complement-Dependent Cytotoxicity (March 26, 2012)
- Automation of a Generic Fluorescent Methyltransferase Activity Assay (March 9, 2012)
- An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators (March 7, 2012)
- Automated Cellular Screening and Characterization of Therapeutic Antibodies for Antibody-Dependent Cell- Mediated Cytotoxicity Utility (February 3, 2012)
- Semi-Automation of a Non-Radioactive Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Assay (Part I) (January 31, 2012)
- Semi-Automation of a Non-Radioactive Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Assay (Part II) (January 31, 2012)
- Automated 384-Well Cell-Based Cytochrome P450 Inhibition Assays Using Cryopreserved Human Hepatocytes in Suspension (January 16, 2012)
- A Simple, Robust Automated Multiplex Assay for Mitochondria Toxicity Testing (December 19, 2011)
- Overcoming the Crabtree Effect is Critical to Mitochondrial Toxicity Testing (October 24, 2011)
- A Flexible and Robust Solution for Automated 384-well HDAC Profiling (July 26, 2011)
- Amplifying Immunoassay Sensitivity with the Optimiser™ Microplate Technology - Repetitive Sample Loading of the Optimiser Microplate Allows for Amplification of Assay Sensitivity from Picogram/mL Levels to Femtogram/mL Levels (June 15, 2011)
- A Homogeneous Assay to Quantify Endogenous AKT Phosphorylation in Human Umbilical Vein Endothelial Cells (February 22, 2011)
- HTRF® Ligand Binding Assay for the Chemokine Receptor CXCR4 (October 29, 2010)
- Automation of a Bioluminescent Live-Cell cAMP Assay for the Pharmacological Evaluation of GPCRs (October 29, 2010)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Induction of Gene Expression and Activity of Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (December 10, 2009)
- Automated ApoTox-Glo Assay to Assess Cell Viability, Cytotoxicity and Apoptosis (March 31, 2009)
- Automating Routine Microplate Pipetting and Dispensing (September 24, 2001)
Цитаты
Научные публикации
Scientific Journals
Assay and Drug Development Technology (1)
SLAS Technology (3)
- Brad Larson, Peter Banks, Hilary Sherman and Mark Rothenberg (2012-01-24) "Automation of Cell-Based Drug Absorption Assays in 96-Well Format Using Permeable Support Systems." SLAS Technology
- Brad Larson, Peter Banks, BioTek Instruments; Jessica L. Kelts, University of Michigan-Flint; James J. Cali, Promega Corporation (2010-07-26) "Automation and Miniaturization of the Bioluminescent UGT-Glo Assay for Screening of UDP-Glucuronosyltransferase Inhibition by Various Compounds." SLAS Technology
- Brad Larson, Peter Banks, BioTek Instruments; James J. Cali, Mary Sobol and Sarah Shultz,Promega Corporation (2010-3-19) "Automated Luminescence-Based Cytochrome P450 Profiling Using a Simple, Elegant Robotic Platform ." SLAS Technology
Trade Journals
Bioscience Technology (1)
Biotech International (1)
Genetic Engineering & Biotechnology News (1)
Lab Manager (1)
Научные постеры
- Assessment of New Developments in ADCC Assays (January 14, 2013)
- An Automated Profiling Application using a Direct, Cell-Based, Target-Compound Interaction Assay for G9a Histone Methyltransferase and Bromodomain Proteins (January 14, 2013)
- Automation of a Homogeneous Proximity Assay for Immunogenicity Testing of Biological Drug Products (January 14, 2013)
- Live-Cell Biosensor Assay Used To Interrogate GPCRs: Comparative Analysis of Biosensor Variants (January 14, 2013)
- Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library (January 14, 2013)
- An Automated, High Throughput Method for the Quantification of Endogenous Cellular Kinase Activity (January 14, 2013)
- Screening for Inhibitors of BRD4 Bromodomain 1 using a Homogeneous Proximity Assay (January 14, 2013)
- An Automated, High Throughput Method for the Quantification of Endogenous Cellular Kinase Activity (September 28, 2012)
- Screening for Inhibitors of BRD4 Bromodomain 1 using a Homogeneous Proximity Assay (September 28, 2012)
- Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library (September 28, 2012)
- Automated High-Throughput Functional Cell-based Bioassays for Blocking Antibodies (May 4, 2012)
- Novel, Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Assays (May 4, 2012)
- Improving Cell-Mediated Cytotoxicity Assessment through the Use of an Automated Luminescent ADCC Assay (March 23, 2012)
- A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity (February 8, 2012)
- Automation of a Generic Fluorescence Methyltransferase Activity Assay (February 8, 2012)
- An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators (February 8, 2012)
- Improving Cell-Mediated Cytotoxicity Assessment through the Use of an Automated Luminescent ADCC Assay (February 8, 2012)
- Automated Solutions for Cellular Screening and Characterization of Therapeutic Antibodies for Antibody-Dependent Cellular Cytotoxicity Utility (February 8, 2012)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (February 8, 2012)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (September 23, 2011)
- A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity (September 23, 2011)
- Ruggedness Testing Including an Evaluation of Automation of a Cell- Based Bioluminescent TNFα Blocker Bioassay (September 23, 2011)
- Automation of a Generic Fluorescence Methyltransferase Activity Assay (September 15, 2011)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (September 15, 2011)
- Automated Compound Profiling Applications for the Assessment of Lead Compound Off-target Effects (July 1, 2011)
- A Flexible and Robust Solution for Automated 384-well HDAC Profiling (May 2, 2011)
- Live-Cell Assay to Interrogate GPCRs by Monitoring cAMP Levels using a Bioluminescent Readout (February 2, 2011)
- A Homogeneous Assay to Quantify Endogenous AKT Phosphorylation in Human Umbilical Endothelial Cells (February 2, 2011)
- Automated 384-Well Cell-Based Cytochrome P450 Inhibition Assays using Cryopreserved Human Hepatocytes in Suspension (February 2, 2011)
- Utility of Automated Drug Transport Assays in 96-Well Format, using Permeable Support Systems (February 2, 2011)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (February 2, 2011)
- Automation of Cell-Based Assays (December 10, 2010)
- Combining Luminescence-based CYP Inhibition Assays and Simple, Robust Instrumentation for Use in Automated Cytochrome P450 Profiling (September 10, 2010)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (September 10, 2010)
- Utility of Automated Drug Transport Assays in 96-Well Format, using Permeable Support Systems (September 10, 2010)
- HTRF® Ligand Binding Assay for the Chemokine Receptor CXCR4 (September 8, 2010)
- Automated Multiplexed Cell-Based Cytochrome P450 Assays (July 12, 2010)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (January 26, 2010)
- Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled Receptor Using A Novel 3-D Cell Culture Technique (January 22, 2010)
- Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity (September 11, 2009)
- A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology (August 13, 2009)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (August 13, 2009)
- Automation of Predictor™ hERG Fluorescence Polarization Assay using Precision™ Automated Pipetting System for Serial Dilution of Small Molecule Drugs for IC50 Determinations (April 29, 2009)
- Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery (April 29, 2009)
- Automated ApoTox-Glo Assay to Simultaneously Assess Cell Viability, Cytotoxicity and Apoptosis (April 29, 2009)
- Automated Triplex Assay to Assess Cell Viability, Cytotoxicity and Apoptosis (February 2, 2009)
- Automating a Lowry Protein Assay with BioTek's Precision™ XS Microplate Sample Processor (June 2, 2004)
- Performance Verification of BioTek's Precision 2000 Using Artel's Multichannel Volume Verification (MVV) System (October 29, 2003)
- Fully Automated Sample Preparation and Nanoelectrospray MS Analysis Using ZipTips, the Precision 2000 and the NanoMate 100 (September 3, 2003)
- A Flexible, Multi-Purpose, Multi-Detector HTS Automated Platform (January 1, 2000)
- Using BioTek’s Precision 2000 Automated Pipetting System for Microarray Sample Preparation (January 1, 2000)